SHARCGS stands for SHort read Assembler based on Robust Contig extension for Genome Sequencing.
SHARCGS is a de novo DNA assembly program that uses 25-40mers and deep sequence coverage to assemble genomes.
It was used for de novo sequencing from Solexa sequencing data of Helicobacter acinonychis.
Source and Documentation
Juliane C. Dohm, Claudio Lottaz, Tatiana Borodina, and Heinz Himmelbauer. SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing. Genome Res. November 2007 17: 1697-1706; Published in Advance October 1, 2007, doi:10.1101/gr.6435207.
Juliane C. Dohm, Claudio Lottaz, Tatiana Borodina, and Heinz Himmelbauer. Substantial biases in ultra-short read data sets from high-throughput DNA sequencing. Nucleic Acids Research Advance Access published on July 26, 2008, doi:10.1093/nar/gkn425