lecture_notes:05-16-2011
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lecture_notes:05-16-2011 [2011/05/16 22:42] eyliaw |
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| = -10 * log_10(1-P(Y=x|Xi=x)) | = -10 * log_10(1-P(Y=x|Xi=x)) | ||
| - | Quality of an alignment: Q1 (quality of read 1), Q2 (quality of read 2), Qa (alignment quality). | + | Quality of our base call based on an alignment: Q1 (quality of read 1), Q2 (quality of read 2), Qa (alignment quality). |
| If we assume that the alignment is perfect: | If we assume that the alignment is perfect: | ||
| * Bases 1 and 2 agree: Q1 + Q2 | * Bases 1 and 2 agree: Q1 + Q2 | ||
| * Bases 1 and 2 disagree: Q1 - Q2? | * Bases 1 and 2 disagree: Q1 - Q2? | ||
lecture_notes/05-16-2011.txt ยท Last modified: 2011/06/13 00:40 by karplus
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