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lecture_notes:04-20-2015

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lecture_notes:04-20-2015 [2015/04/25 02:58]
calef [Meraculous algorithm]
lecture_notes:04-20-2015 [2015/04/25 03:01]
calef [Installation]
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   * Searches unaligned reads as potential gap-closers using mate-pair data   * Searches unaligned reads as potential gap-closers using mate-pair data
 =====Meraculous limitations===== =====Meraculous limitations=====
-  * The assembler relies on data with high quality in order to avoid error correction+  * The assembler relies on data with high quality in order to avoid error correction, also requires high coverage
   * Initial release did not support polyploid genome assembly due to allowing for linear subgraphs of the de Bruijn graph only   * Initial release did not support polyploid genome assembly due to allowing for linear subgraphs of the de Bruijn graph only
-  * Low memory footprint+  * High disk space usage
 =====User experience===== =====User experience=====
   * Requires an array of other scripts in other languages   * Requires an array of other scripts in other languages
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   * Tested the program in small dataset and obtained contigs   * Tested the program in small dataset and obtained contigs
 =====Installation===== =====Installation=====
-  * Main issue was get all dependencies together  +  * Main issue was new version of GCC and getting ​all the dependencies together ​~16 hrs  
-  * There was one non-standard perl mode needed+  * There was one non-standard perl module ​needed 
 +  * Files with carriage returns
   * Some scripts contain error but they aren't hard to fix.   * Some scripts contain error but they aren't hard to fix.
 =====Running Meraculous===== =====Running Meraculous=====
lecture_notes/04-20-2015.txt · Last modified: 2015/04/25 03:07 by calef