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====== Karyotyping ====== Karyotyping should be done during the metaphase cycle, when the chromosomes are distinct and easily counted. To obtain a sample with a good number of cells in metaphase, typically blood or skin cells are collected. Some drugs are used to stimulate division and lock cells into metaphase: see [[http://arbl.cvmbs.colostate.edu/hbooks/genetics/medgen/chromo/cytotech.html|Preparing a Karyotype]].